| Description: |
VCAM-1 is a cell surface sialoglycoprotein expressed by
cytokine activated endothelium. The protein has a
number of functions including the regulation of leukocyte
migration, leukocyte-endothelial cell adhesion and signal
transduction and may play a role in a number of
inflammatory diseases.
RANDOX recombinant VCAM comprises a 674 amino
acid fragment (25-698) corresponding to the mature
extracellular VCAM protein and is expressed in E. coli
with an amino-terminal hexahistidine tag. This product is
for research use only and is not intended for diagnostic or
therapeutic use.
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| Form:
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Liquid.
Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8,
50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol
Blue, 2.5% Glycerol).
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| Purity:
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Single band on Western blot
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| References:
|
Steeber, D. A & Tedder, T.F. (2000) Immuno. Res. 22(2-
3) : 299- 317.
Albelda, S.M et al. (1994) FASEB J. 8(8): 504-512.
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| Datasheet: |
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