| Description: |
RANTES (acronym for Regulated upon Activation,
Normal T-cell Expressed, and presumably Secreted) is a
member of the beta (C-C) chemokine subfamily and is
predominantly produced from T cells and platelets.
RANTES has been shown to be a chemoattractant factor
for monocytes, CD4+/CD45RO+ T lymphocytes and
basophils. It has also been shown to induce the
proliferation and activation of killer cells and may act as a
HIV suppressive factor.
RANDOX recombinant RANTES comprises a 68 amino
acid fragment (24-91) corresponding to the mature RANTES
protein and is expressed in E. coli with an amino-terminal
hexahistidine tag. This product is for research use only and is
not intended for diagnostic or therapeutic use.
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| Form:
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Liquid.
Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8,
50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol
Blue, 2.5% Glycerol).
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| Purity:
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Single band on Western blot
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| References:
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Schall, T.J. et al., (1988) J. Immunol. 141 (3): 1018-1025.
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| Datasheet: |
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