| Description: |
L-Selectin belongs to a family of divalent cationdependent
carbohydrate-binding glycoproteins or
adhesion molecules. L-Selectin is expressed
constitutively on lymphocytes, monocytes and
granulocytes and interacts specifically with carbohydrate
groups on activated endothelial cells. L-Selectin may be
shed by proteolytic cleavage and circulating levels in
biological fluids may be used as an indicator of various
pathological conditions.
RANDOX recombinant human L-selectin comprises a
294 amino acid fragment (39-332) corresponding to the
mature L-Selectin extracellular domain and is expressed
in E. coli with an amino-terminal hexahistidine tag. This
product is for research use only and is not intended for
diagnostic or therapeutic use.
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| Form:
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Liquid.
Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8,
50mM DTT,1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue,
2.5% Glycerol).
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| Purity:
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Single band on Western blot.
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| References:
|
Tedder, T.F et al. (1990) J. Immunol. 144 (2): 532-540.
Schleiffenbaum, B. et al. (1992) J. Cell Biol. 119 (1): 229-
238.
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| Datasheet: |
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