Home Recombinant Proteins Integrin-Linked Kinase 1 Integrin-Linked Kinase Protein

Integrin-Linked Kinase Protein

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RCP9198 10µg £88.46

Human Recombinant Protein Specification

Description: Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage-independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies. RANDOX recombinant ILK1 comprises a 452 amino acid fragment (1-452) corresponding to the mature ILK1 full-length protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
Application: ELISA, Western Blot, Dot Blot, Immunohistology chemistry, Immunoassays, Development of Rapid tests and other immunoassay,
Form: Liquid
Purity: >95% by SDS-PAGE
References: Hannigan G.E. et al Nature. 1996. 379 (6560) : 91-6. Marotta A. et al, BJC 2003 88 :1755-1762
Datasheet: PDF download