| Description: |
Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits. Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, inhibins are also thought to play a role in the control of gametogenesis, and embryonic and foetal development. RANDOX recombinant Inhibin A alpha subunit comprises a 134 amino acid fragment (233-366) corresponding to the mature Inhibin alpha subunit protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
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| Form:
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Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).
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| Purity:
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Single band on Western blot.
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| References:
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Burger, H.G. (1988) J. Endocrinol. 117(2) : 159-160. Canick, J.A & MacRae, A.R. (2005) Semin. Perinatol. 29(4) : 203-208.
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| Datasheet: |
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