| Description: |
VEGFR-1 belongs to a family of five receptor tyrosine kinase receptors that are specific to a number of angiogenic factors including VEGF and PDGF, and are therefore thought to play a role in the angiogenic process. VEGFR-1 is expressed in two forms, predominantly on endothelial cells, giving rise to a full-length membrane bound receptor and a truncated soluble receptor. Elevated levels of the soluble form of this VEGF receptor may be used in the diagnosis of pathological conditions. RANDOX recombinant VEGFR-1 comprises a 298 amino acid fragment (31-328) corresponding to the IgGlike domains 1-3 from the mature soluble VEGFR protein. VEGF-R1 is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
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| PH:
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7.2
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| Application:
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ELISA, Western Blot, Dot Blot, Immunohistology chemistry, Immunoassays, Development of Rapid tests and other immunoassay,antibody recognition assays
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| Buffer:
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20mM Phosphate, 150mM Sodium Chloride, pH 7.2
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| Format:
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Ig Fraction
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| Host:
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Sheep
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| Immunogen:
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Recombinant Human VEGFR1
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| Lot:
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RS867-11
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| Preservative:
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0.09% Sodium Azide
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| Storage:
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≤ -20C, avoid repeated freeze/thaw cycles
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| References:
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Starovasnik, M. A et al. (1999) J. Mol. Biol. 296 (3) : 531-544. Kanno, S. et al. (2000) Oncogene 19 (17) : 2138-2146.
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| Datasheet: |
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