| Description: |
This nuclear receptor functions as a transcription factor
and plays an important role in controlling differentiation
and fatty acid metabolism. Activation of this receptor
appears to be vital in modulating the expression of
metabolic control proteins and consequently controlling
fatty acid metabolism in cardiac muscle. This marker
may be a useful drug target for therapeutic intervention in
cardiac disease. PPARĪ³ is also involved in the
pathogenesis of important metabolic disorders such as
obesity and non-insulin-dependent diabetes (NIDDM).
RANDOX recombinant human PPARĪ³ is expressed in
E. coli with an amino-terminal hexahistidine tag. This
product is for research use only and is not intended for
diagnostic or therapeutic use
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