| Description: |
GSTO1 is a member of the theta class glutathione S-transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. RANDOX recombinant GSTO1 comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 mature protein, which is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
|
| Concentration:
|
11.08 mg/ml (U.V. abs at 280nm)
|
| Method Of Production:
|
In vitro cell culture using standard DMEM media supplemented with foetal bovine serum of a USDA approved origin
|
| Method of Purification:
|
Protein A Chromatography
|
| PH:
|
7.2
|
| Application:
|
ELISA, Western Blot, Dot Blot, Immunohistology chemistry, Immunoassays, Development of Rapid tests and other immunoassay,antibody recognition assays
|
| Buffer:
|
PBS at pH 7.2 - 7.59
|
| Footer:
|
This product as supplied is intended for research applications only, not for use in therapeutic or diagnostic applications
|
| Format:
|
Purified Monoclonal Antibody
|
| Host:
|
Sheep
|
| Immunogen:
|
wtGST peptide-BTG
|
| Preservative:
|
0.1% Sodium Azide
|
| Storage:
|
+2 - + 8 ºC
|
| References:
|
Withbread, A. K. et al., Methods in Enzymology 2005; 401: 78-99 Kölsch, H. et al., Neurology 2004; 63 : 2255-2260
|
| Datasheet: |
|
