| Description: |
Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins (14-15kDa) that bind
long chain fatty acids, their CoA derivatives, bilirubin, organic anions and other small hydrophobic molecules.
Their primary role is the regulation of fatty acid uptake and intracellular transport. (1) To date, nine different fatty
acid binding proteins have been identified and named by tissue of first discovery or numerically by gene. (1-9)
Fatty acid binding proteins are abundantly present in numerous cell types and due to their small size, can rapidly
leak from cells after trauma. As such, the measurement of elevated levels of fatty acid binding proteins in serum
can be used as a diagnostic marker to monitor the extent of tissue damage.
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| Method Of Production:
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In vitro cell culture using standard DMEM media supplemented with foetal bovine serum of a USDA approved origin
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| Method of Purification:
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Protein A Chromatography
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| PH:
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7.2
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| Application:
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ELISA, Western Blot, Dot Blot, Immunohistology chemistry, Immunoassays, Development of Rapid tests and other immunoassay,antibody recognition assays
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| Buffer:
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PBS at pH 7.2 - 7.59
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| Footer:
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This product as supplied is intended for research applications only, not for use in therapeutic or diagnostic applications
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| Format:
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Purified Monoclonal Antibody
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| Host:
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Sheep
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| Immunogen:
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rh FABP (3)
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| Lot:
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P1160
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| Preservative:
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0.1% Sodium Azide
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| Related:
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RCP9101, rhFABP (3),
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| Storage:
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+ 2 - + 8°C
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| References:
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1. Chmurzynska A. J. Appl. Genet. 2006, 47(1): 39-48.
2. Entrez Gene : FABP1 fatty acid binding protein1, liver
3. Lieberman JM et al. Surgery. 1997, 121(3): 335-342.
4. Lescuyer P et al. Mol Diagn. 2005, 9(1): 1-7
5. Zimmerman A W & Veerkamp JH. Cell Mol Life Sci 2005, 59(7): 1096-1116
6. Siegenthaler G et al.. Biochem Biophys Res Commun. 2003, 190(2): 482–7
7. Kurz M et al. Proteins. 2003, 50(2): 312-328.
8. Wunderlich, MT. et al. J Neurol. 2005, 252 (6): 718-724.
9. Narayana V et al. J. Neurochem. 2004, 63 : 2010-2013
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| Datasheet: |
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