| Description: |
Interleukin-4 is a pleiotropic cytokine produced primarily
by activated T lymphocytes, basophils and mast cells.
Multiple immune response-modulating functions are
performed by IL-4 on a variety of cell types and it has an
important role in the regulator of isotype switching,
induction of IgE production in B lymphocytes and
differentiation of precursor T helper cells. IL-4 binds to
both membrane-bound and secreted soluble IL-4
receptors.
RANDOX recombinant IL-4 comprises a 129 amino acid
fragment (25-153) corresponding to the mature IL-4
protein and is expressed in E. coli with an amino-terminal
hexahistidine tag. This product is for research use only
and is not intended for diagnostic or therapeutic use.
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| Synonyms:
|
BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4,MGC79402, Binetrakin, Pitrakinra.
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| Application:
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Lindemann A. & Mertelsmann R. (1993) Cancer Invest. 11(5): 609- 623.
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| Buffer:
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Carrier free format presented in 50% glycerol buffered with saline or Tris
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| Form:
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Liquid
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| Purity:
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>95% by SDS-PAGE
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| Storage:
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≤-20°C
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| References:
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Ohara, J. (1989) Year Immunol. 5 : 126-159.
Beckmann, M.P. et al. (1992) Chem. Immunol. 51 : 107-
134
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| Datasheet: |
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