| Description: |
Tricyclic antidepressants (TCAs) are a group of drugs that contain a characteristic three ringed nucleus structure. They have been used in the treatment of various forms of depression, anxiety disorders, attention deficit hyperactivity disorder and enuresis in children and as an adjunct to analgesics for certain chronic and neuropathic pain syndromes. Whilst therapeutic drug monitoring (TDM) of TCA’s is well established in the treatment of depression, TCA overdose remains the most common cause of death from prescription drugs(1, 2).
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| Format:
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The conjugate is supplied as a concentrate. Dilute as required and use working strength conjugate immediately after dilution
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| Specificity:
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Each conjugate comprises antigen covalently bound to horseradish peroxide and is suitable as a tracer in immunoassay development.
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| Storage:
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+2-+8C for up to 3 months / <20C for long term storage
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| References:
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1. Haddad L.M. Managing tricyclic antidepressant overdose. Am. Farm. Physician. 1992, 46 (1): 153-159. 2. Pimentel L. and Trommer L-Cyclic antidepressant overdoses. A review. Emerg. Med. Clin. North. Am. 1994, 12 (2): 533-547.
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