Home Conjugates Drugs of Abuse Opiates Buprenorphine Buprenorphine(3)-HRP


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HRP9663 0.5ml

HRP Tracer Specification

Name: Buprenorphine(3)-HRP
Description: Buprenorphine is a highly lipophylic derivative of the Thebaine and is a powerful partial agonist analgesic. It is effective in treating pain and is 25 to 40 times more potent than morphine. Since the 1980s it has been widely prescribed for the treatment of moderate to severe pain and in anaesthesiology for premedication and/or anaesthetic induction. Soon after buprenorphine became clinically available there were reports of abuse as it was frequently used as the drug of choice when there was a shortage of heroin supplies. Studies then showed that when buprenorphine was used for opiate dependence treatment the withdrawal syndrome on discontinuing buprenorphine was milder than methadone and that fewer symptoms emerged during detoxification with buprenorphine.
DilnFactor: 20
Format: The conjugate is supplied as a concentrate. Dilute as required and use working strength conjugate immediately after dilution
Specificity: Each conjugate comprises antigen covalently bound to horseradish peroxide and is suitable as a tracer in immunoassay development.
Storage: +2 - +8 for up to 3 months / -20°C for long term storage
References: 1. Debrabandere L., Van Boven M. and Daenens P. Development of a fluoroimmunoassay for the detection of buprenorphine in urine. J Forensic Sci. 1995, 40(2): 250-253. 2. Cirimele V, Kintz P, Lohner S and Ludes B. Enzyme immunoassay validation for the detection of buprenorphine in urine. J Anal Toxicol. 2003, 27(2): 103-105. 3. Euro-Methwork Quest for Quality Buprenorphine critical questions examined. (Rev. 17-Oct-05) (http://www.q4q.nl/methwork/BPN/bpn.htm).